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Amazon.com (0670063584) 21 reviews
Amazon.com (0713997249) 21 reviews
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J Craig Venter

A Life Decoded

Craig Venter has caused quite a stir in the scientific community, in that he turned the sequencing of the Human Genome into something of a race. He has also been criticised for his part in the commercialisation of the genome. In A Life Decoded:My Genome:My Life Venter tells his side of the story.

Taking a break from his job as a medic in the Vietnam war, Venter went for a swim, but had to swim back with one arm, using the other to hold off a poisonous sea-snake - you quickly find out the way Venter does things.

Venter entered the academic world, but was always keen to get ahead, and was soon running his own department. He became impatient with the delays and bureaucracy of government funding and so looked for funding from commercial sources. He wanted to be at the forefront of research, and would try to get the best out of his team, overcoming the teething troubles of the latest equipment. Unfortunately this meant that his results sometimes couldn't be reproduced by others, leading to doubts about their reliability. Venter soon was aiming at the prize of the Human Genome Sequence. His 'shotgun' technique offered the prospect of being able to sequence the whole genome, rather than labouring away with a part at a time. This meant that the sequencing was done several years ahead of schedule.

On the issue of commercialisation, Venter implies that he always aimed to make his results as widely available as possible, but would accept commercialisation if that meant that he could proceed faster. No doubt those interested in this aspect of the story will want to read other books on the subject, but this one certainly gives an important viewpoint on the human genome project.

Amazon.com info
Hardcover 400 pages  
ISBN: 0670063584
Salesrank: 423572
Weight:1.5 lbs
Published: 2007 Viking Adult
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Amazon.co.uk info
Hardcover 400 pages  
ISBN: 0713997249
Salesrank: 330003
Weight:1.63 lbs
Published: 2007 Allen Lane
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Amazon.ca info
Hardcover 400 pages  
ISBN: 0670063584
Salesrank: 190635
Weight:1.5 lbs
Published: 2007 Viking USA
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Product Description
The triumphant true story of the man who achieved one of the greatest feats of our era—the mapping of the human genome

Growing up in California, Craig Venter didn’t appear to have much of a future. An unremarkable student, he nearly flunked out of high school. After being drafted into the army, he enlisted in the navy and went to Vietnam, where the life and death struggles he encountered as a medic piqued his interest in science and medicine. After pursuing his advanced degrees, Venter quickly established himself as a brilliant and outspoken scientist. In 1984 he joined the National Institutes of Health, where he introduced novel techniques for rapid gene discovery, and left in 1991 to form his own nonprofit genomics research center, where he sequenced the first genome in history in 1995. In 1998 he announced that he would successfully sequence the human genome years earlier, and for far less money, than the government-sponsored Human Genome Project would— a prediction he kept in 2001.

A Life Decoded is the triumphant story of one of the most fascinating and controversial figures in science today. In his riveting and inspiring account Venter tells of the unparalleled drama of the quest for the human genome, a tale that involves as much politics (personal and political) as science. He also reveals how he went on to be the first to read and interpret his own genome and what it will mean for all of us to do the same. He describes his recent sailing expedition to sequence microbial life in the ocean, as well as his groundbreaking attempt to create synthetic life. Here is one of the key scientific chronicles of our lifetime, as told by the man who beat the odds to make it happen.
 
Debugging the Code *****
If one were to choose a perfect specimen of the old-fashioned American can-do rugged individual one has to look no further than the author, Craig Venter. "Only in America" (as the saying goes) was such a gigantic undertaking possible. It required not only an entrepreneurial setting and an educated cadre of experts but also the drivers of the modern age: Capitalism and Science. The two are eerily similar with their redundancy, messiness, elements of greed, enormous failures and astounding successes. They have revolutionized the world and if Venter is correct, this influence will only grow stronger.

Some have commented in great length on the ego within these pages. What they do not acknowledge is that a quiet, compromising, timid man could not have accomplished what he did. Venter was a tinkerer even as a boy, someone with strong opinions, drive, likes and dislikes. The path from troubled teen to doctor and scientist was dwarfed by the HGP (Human Genome Project). The veil was ripped from our fantasy world of peaceful scientists working solely for the good of mankind. Politics reared its ugly head and one can say that the goal was accomplished despite - certainly not because - of the powers that wannabe in D.C. The funding system wherein annual grants must be justified ("spend it or lose it") was at the heart of the majority of disputes. The lack of incentive to trim, economize and develop more economical solutions does not exist in the land of federal grants.

Venter does a good job of scientific explication for the "educated layman" but one has to wonder how many of the humongous words and dense commentaries were given the once over. Diagrams explaining some of the terms would have been helpful. The shaded explanations of his own DNA were interesting and though he holds a materialistic view of life, he is not a genetic determinist in the style of Dawkins and Company. He believes that we and our social constructs (religion, family, education, science, philosophy) are more than the pre-determined product of a collection of chemical reactions. Despite his many detractors, Venter continues practicing cutting edge beneficial science, especially in a quest for synthetic life forms that would provide pollution-free energy, power and food.

The reader is left wondering about his last project, the creation of a synthetic life genome with a couple of thousand base pairs. In 2008, his institute announced that the bacterium Mycoplasma genitalium with over half a million base pairs had been created and this was only the beginning. My Grade - A
 
The Unreasonable Man; or "what's all this bio-babble?" ***
This autobiography is at times (a) demonstration of G.B.Shaw's adage that "The reasonable man adapts himself to the conditions that surround him... The unreasonable man adapts surrounding conditions to himself... All progress depends on the unreasonable man.", (b) morality tale on why monopolies (government bureaucracies) are bad even if well-intentioned, (c) gripping first-hand accounts of deftly sidestepping Naval bureaucracy and surviving despair in Vietnam, and (d) proof of my thesis advisor's adage that "research is a social enterprise". With high doses of more bio-babble than I could or would grasp sometimes.
 
mind blowing science *****
I found the book in a secondhand book store after christmas and took a gamble as my holiday read. I knew of the author's monumental human genome work (being a scientist myself) and only very vaguely what else he had done in his career It was well worth the money. Two days on I had experienced one hellishly good thrill ride. So what if the author can do no wrong in his opinion. I loved it; a bit of war time experience saving lives (it felt like you were there), a bit of sailing (gripping sailor yarns), a huge heap of mind blowing science and few stabs at folks - what more could you want. I finished wanting more and all that was missing was a few nobel prizes. As I told my wife "Do I want to be like Craig?" No, but I do want to strive to achieve more. The author has lived many lives and they all have been incredibly interesting and inspiring. Anyone that is willing to bare his own genes and more deserves kudos. This book inspired me to read other perspectives too. Another secondhand book store this past weekend yielded a signed Harold Varmus autobio and I have to say its starting slow. Can it surpass A LIFE DECODED?
 
Craig told me about his book, so I had to read it! *****
I was relaxing on my boat after a day of sailing, enjoying a beer, while I watched this bald guy park his big power boat in the marina slip next to mine. He looked like the new guy in the marina, so I called out "looks like moving day!" He said it was, so I walked over and introduced myself. He told me his name was Craig, and as I did a double-take, I asked him if he was Craig Ventner. He politely corrected me and said "Venter." Wow! I told him how my wife and I saw the Discovery show "Decoding the Oceans", and asked him where Sorcerer II was, and he told me she was on a new expedition. There I was having a neighborly conversation with my new neighbor - a real live superstar! (I'm an engineer, sort of a nerd, so to me Craig is a superstar). I'm also a CEO and I enjoy reading about successful people. Armand Hammer, Chuck Yeager, Lee whatshisname, The Donald's "Art of the Deal", so I was intrigued when Craig suggested that I read his book "Decoding Life" to learn more about genomics. So, I did. Just finished it in fact. Couldn't put it down. Anyway, I left Craig to finish cleaning up his boat and went to pick up the pizza that I had ordered. On my way back, as I walked through the marina parking lot, what do I see?...a beautiful black Tesla roadster, and I immediately know who owns it. Back on the dock, as I walked past Craig, where he is sorting his dock lines, I ask "hey Craig, is that your Tesla up there in the parking lot?" Of course it's his. I knew it. He loves it, all electric hotrod, so fast it scares him, he says. So, naturally I offer to share my pizza with him, since its around dinner time now. Craig smiles and says the offer is tempting, but his wife is waiting at home for him, and we part. So, back on my boat, I'm so excited, I call my wife to tell her I just met Craig Venter, no Venter, not Ventner. As I'm talking to my wife I hear a knock on my boat, and guess who hands me a bottle of wine? Thanks Craig, I say, as I tell my wife Craig Venter just came by and offered me a bottle of wine he had left in the cooler on his boat.

Craig is one of us. He belongs to us. He is a National Treasure. Our brother that we share 99.5% of our DNA with, and he is of the most gifted human beings of our time. I'm thrilled and honored to have met him because its not every day you meet a guy like that with a mind so creative and flexible to be able to solve one of mankind's most complex puzzles, and yet be so thoughtful and warm a human being. Thanks Craig, I raise my glass and toast you, may your CETP gene help you live long and prosper!

B. Downing
 
Damned generation *
You fools have no idea what you are doing when you rate this book highly. This is the guidebook to DNA patenting for universal enslavement, organ harvesting, stem cell harvesting, living weapons testing experiments. This man is your evil task master and he's so confident that you're stupid enough to love your enslavement that he publicly announces in a book how he's going to get away with it. Morons. You deserve your lot in what's coming. I do not pity you whatsoever. Suffer.
 
Meet the controversial scientist who deciphered the human genome ****
J. Craig Venter says he is one of the "leading scientists of the 21st century," and he is. Venter is a brilliant visionary and pioneer in genomic research. He was first to decode the full DNA of a living organism, the bacterium Haemophilus influenzae. Later, Venter moved up significantly in scientific class by completing the DNA sequence of the human genome. Feverishly ambitious, he is now researching ocean genomes in hopes of finding new fuel sources and of becoming the first scientist to create artificial life. Venter does nothing halfway, hence his designation by Time magazine as one of the world's 100 most influential people. Yet, in scientific circles, he has also earned some disdain as an egotistical "wild man of biotech." Many scientists see his use of his own DNA in the human genome project as a shocking lack of scientific decorum. He comes across, in his own words, as narcissistic. This self-absorption, and his pervasive portrayal of himself as an altruistic purist constantly battling bureaucratic philistines, interferes with his story about how he cracked the human genome code. Clearly, it's not easy being a genius, but it sure is interesting, and so getAbstract recommends Venter's account of his scientific achievements.
 
Build me an alien soon Craig - you should have been in Star Trek *****
Perhaps I'm being unkind but Craig is one of those people whose every life experience somehow has to surpass those of anyone else, you know the sort, his story always tops yours, his anecdote is always the ultimate. He's done it faster, bigger and better than you. But that's my only complaint - this is a fascinating biography set in the fast growing field
of molecular biology and it must be well written because it held my attention despite my complete ignorance of biology, molecular or otherwise. Of course its all about Craig and the essential point is that he pioneered the full sequencing/reading of a human genome (program code). Hithertoo I had the impression that Craig was an unscrupulous villain tryng to steal the secrets of our DNA and lock them up for profit. This book sets the record straight. Craig has been sinned against - on the one hand by greedy capitalists who sought to exploit him - and on the other by petty bureaucrats abetted by jealous academics who sought to stiffle him or steal his laurels. No wonder Craig has to pop off on his latest yacht every now and again and have a larger scale man v. nature adventure - but you can skip his yacht excursions without compromising the rest of the book. Finally, I'm sorry to say that Big Jim Watson doesn't emerge very well from this tale. I've long harboured (Cold Spring Harbour ?) a fond image of Watson and Crick rushing into the Eagle that famous Saturday lunchtime in January 1953 and woofing back pints of Abbott to celebrate discovering the meaning of life - and no one in the pub knew what they were talking about! Now my image is a bit dashed, as the "father" of DNA, Jim was no help to Craig's decodering endevours at all - it looks like he was obstructive and possibly devious. Another hero struck off. Good job Craig can take his place. This book is about Craig and molecular biology so far - his next book is going to be about the future. Bring it on !
 
Life in the fast lane *****
Although essentially a biography of Craig Venter, the book is more than this. It is an up-to-date account of the very latest developments in genomic science. The book is also one side of the somewhat accrimonious dispute regarding the ownership of the human genome. Venter, the enfent-terrible of science, gives a detailed and exciting blow by blow account of the race to sequence the human genome. On one side the entrepreneurs and on the other side the government sponsored consortium determined to keep the genome in the public domaine. Although primarily a book for the initiated, this is a fast-moving thriller written by a born story-teller. At times the science is challenging for those without prior knowledge or interest in the field. Throughout however, there is Venter at the sharp-end of science continually pressing forward with new ideas, breaking all the existing rules and inventing new ones as he goes. Throughout the book there are clever references on the side, to various genes from Venters own genome which he has sequenced. Venter gives a description of the relevant gene and the implications of the particular genetic variant in terms of his future health. This is in itself unique.

Venter is a man driven, both in the laboratory and behind the wheel of his expensive yachts which he sails with a passion. There is only one thought in Venter's mind- success at any price. This book is a must for anyone wanting a current perspective of genomic science written by one of the leaders in the field.

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