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Amazon.com (0713997249) 23 reviews
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Amazon.co.uk (0670063584) 7 reviews
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J Craig Venter

A Life Decoded

Craig Venter has caused quite a stir in the scientific community, in that he turned the sequencing of the Human Genome into something of a race. He has also been criticised for his part in the commercialisation of the genome. In A Life Decoded:My Genome:My Life Venter tells his side of the story.

Taking a break from his job as a medic in the Vietnam war, Venter went for a swim, but had to swim back with one arm, using the other to hold off a poisonous sea-snake - you quickly find out the way Venter does things.

Venter entered the academic world, but was always keen to get ahead, and was soon running his own department. He became impatient with the delays and bureaucracy of government funding and so looked for funding from commercial sources. He wanted to be at the forefront of research, and would try to get the best out of his team, overcoming the teething troubles of the latest equipment. Unfortunately this meant that his results sometimes couldn't be reproduced by others, leading to doubts about their reliability. Venter soon was aiming at the prize of the Human Genome Sequence. His 'shotgun' technique offered the prospect of being able to sequence the whole genome, rather than labouring away with a part at a time. This meant that the sequencing was done several years ahead of schedule.

On the issue of commercialisation, Venter implies that he always aimed to make his results as widely available as possible, but would accept commercialisation if that meant that he could proceed faster. No doubt those interested in this aspect of the story will want to read other books on the subject, but this one certainly gives an important viewpoint on the human genome project.

Amazon.com info
Hardcover 400 pages  
ISBN: 0670063584
Salesrank: 640547
Weight:1.5 lbs
Published: 2007 Viking Adult
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Amazon.co.uk info
Hardcover 400 pages  
ISBN: 0713997249
Salesrank: 342166
Weight:1.63 lbs
Published: 2007 Allen Lane
Amazon price £23.75
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Amazon.ca info
Hardcover 400 pages  
ISBN: 0670063584
Salesrank: 219927
Weight:1.5 lbs
Published: 2007 Viking USA
Amazon price CDN$ 31.00
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Product Description
The triumphant true story of the man who achieved one of the greatest feats of our era—the mapping of the human genome

Growing up in California, Craig Venter didn’t appear to have much of a future. An unremarkable student, he nearly flunked out of high school. After being drafted into the army, he enlisted in the navy and went to Vietnam, where the life and death struggles he encountered as a medic piqued his interest in science and medicine. After pursuing his advanced degrees, Venter quickly established himself as a brilliant and outspoken scientist. In 1984 he joined the National Institutes of Health, where he introduced novel techniques for rapid gene discovery, and left in 1991 to form his own nonprofit genomics research center, where he sequenced the first genome in history in 1995. In 1998 he announced that he would successfully sequence the human genome years earlier, and for far less money, than the government-sponsored Human Genome Project would— a prediction he kept in 2001.

A Life Decoded is the triumphant story of one of the most fascinating and controversial figures in science today. In his riveting and inspiring account Venter tells of the unparalleled drama of the quest for the human genome, a tale that involves as much politics (personal and political) as science. He also reveals how he went on to be the first to read and interpret his own genome and what it will mean for all of us to do the same. He describes his recent sailing expedition to sequence microbial life in the ocean, as well as his groundbreaking attempt to create synthetic life. Here is one of the key scientific chronicles of our lifetime, as told by the man who beat the odds to make it happen.
 
Interesting view from one of the father of genomics ****
Book is well written and offers a personal view of the story of how the human was genome was decoded. Interspersed with various observations of his own genetic code, Venter tells his life and the interactions with the other players in the public effort. His contempt for the power / politics they play rather than the science is clear. You may not like his character but you will admire his drive to solve the problem
 
Congratulations! *****
While I had to make a considerable effort to understand, even in part, the inner workings of molecular biology, the book is a living testimony to the adage that the least done by the people is better than the most done by a government. Venter had proven that only individuals with indomitable spirit can and do cross new borders, reach out beyond the horizons, do it faster, better, for a lot less (public) money.

Those who find the book, at times, hard going, are richly rewarded in the very last chapter, which for all but the faint at heart, renews hope in the human potential and endeavour. Thank you, Dr. Venter.


Stan Law is the author of ASIN:0973187255 The Avatar Syndrome (Prequel to Headless World) and more than 20 books, some available on the Amazons.
 
Debugging the Code *****
If one were to choose a perfect specimen of the old-fashioned American can-do rugged individual one has to look no further than the author, Craig Venter. "Only in America" (as the saying goes) was such a gigantic undertaking possible. It required not only an entrepreneurial setting and an educated cadre of experts but also the drivers of the modern age: Capitalism and Science. The two are eerily similar with their redundancy, messiness, elements of greed, enormous failures and astounding successes. They have revolutionized the world and if Venter is correct, this influence will only grow stronger.

Some have commented in great length on the ego within these pages. What they do not acknowledge is that a quiet, compromising, timid man could not have accomplished what he did. Venter was a tinkerer even as a boy, someone with strong opinions, drive, likes and dislikes. The path from troubled teen to doctor and scientist was dwarfed by the HGP (Human Genome Project). The veil was ripped from our fantasy world of peaceful scientists working solely for the good of mankind. Politics reared its ugly head and one can say that the goal was accomplished despite - certainly not because - of the powers that wannabe in D.C. The funding system wherein annual grants must be justified ("spend it or lose it") was at the heart of the majority of disputes. The lack of incentive to trim, economize and develop more economical solutions does not exist in the land of federal grants.

Venter does a good job of scientific explication for the "educated layman" but one has to wonder how many of the humongous words and dense commentaries were given the once over. Diagrams explaining some of the terms would have been helpful. The shaded explanations of his own DNA were interesting and though he holds a materialistic view of life, he is not a genetic determinist in the style of Dawkins and Company. He believes that we and our social constructs (religion, family, education, science, philosophy) are more than the pre-determined product of a collection of chemical reactions. Despite his many detractors, Venter continues practicing cutting edge beneficial science, especially in a quest for synthetic life forms that would provide pollution-free energy, power and food.

The reader is left wondering about his last project, the creation of a synthetic life genome with a couple of thousand base pairs. In 2008, his institute announced that the bacterium Mycoplasma genitalium with over half a million base pairs had been created and this was only the beginning. My Grade - A
 
The Unreasonable Man; or "what's all this bio-babble?" ***
This autobiography is at times (a) demonstration of G.B.Shaw's adage that "The reasonable man adapts himself to the conditions that surround him... The unreasonable man adapts surrounding conditions to himself... All progress depends on the unreasonable man.", (b) morality tale on why monopolies (government bureaucracies) are bad even if well-intentioned, (c) gripping first-hand accounts of deftly sidestepping Naval bureaucracy and surviving despair in Vietnam, and (d) proof of my thesis advisor's adage that "research is a social enterprise". With high doses of more bio-babble than I could or would grasp sometimes.
 
mind blowing science *****
I found the book in a secondhand book store after christmas and took a gamble as my holiday read. I knew of the author's monumental human genome work (being a scientist myself) and only very vaguely what else he had done in his career It was well worth the money. Two days on I had experienced one hellishly good thrill ride. So what if the author can do no wrong in his opinion. I loved it; a bit of war time experience saving lives (it felt like you were there), a bit of sailing (gripping sailor yarns), a huge heap of mind blowing science and few stabs at folks - what more could you want. I finished wanting more and all that was missing was a few nobel prizes. As I told my wife "Do I want to be like Craig?" No, but I do want to strive to achieve more. The author has lived many lives and they all have been incredibly interesting and inspiring. Anyone that is willing to bare his own genes and more deserves kudos. This book inspired me to read other perspectives too. Another secondhand book store this past weekend yielded a signed Harold Varmus autobio and I have to say its starting slow. Can it surpass A LIFE DECODED?
 
It's not easy being a genius. *****
It's not easy being a genius. Venter describes how he cracked the human genome, but also gives a terribly depressing account of the politics of big science.

Ever the maverick, Venter started out as a high school drop out Californian surf dude that gets drafted to Vietnam. He escapes the front line and traumatically learns medical science treating hundreds of maimed soldiers. After 'nam he gets into research and begins his path to sequencing the genome and to world fame.

Venter inserts boxes in the text to explain the meaning of his own genetic code to afford valuable understanding of the decoding of the genome. This provides helpful insight into genetic links to a number of ailments.

The Bad Boy of Biology continues to raise debate today. His latest mission is in designing new life-forms, with the possibility of defeating global warming. The book is a good read, though Venter's ego comes through on many an occasion
 
Science is politics by other means *****
If you ever were mistaken in thinking that science was the rational pursuit of objective knowledge, this autobiography will finally cure you of that misconception. This is a brilliant account of how one man's drive to be the best in science sets him against most of his contemporaries, including the Nobel Laureate James Watson. Venter's grant applications for cutting-edge work are blocked through jealousy, hatred and spite; and Venter is not exempt from political motivation in his various ventures.

Part of Venter's genius was to realise early on that great strides forward in genetic research would only come through using the most up-to-date robotics and computing to automate sequencing. This set everyone else against him, partly because their slow methods of work enabled each to gain fame for his or her own bit of DNA: a process and scientific world blown apart by Venter.

Venter intersperses his account with a running commentary on his sailing exploits, which breaks up the narrative. Some of the science could have been explained more simply, but you can hum through the bits you don't know because the basic story steams on. Riveting.
 
Fantastic *****
Ok, Craig Venter is not short of a trumpet or two for himself to blow, but what an amazing insight into the race to map the genome and a glimpse into what these genomicists do! It's a high speed tour with lots of frank comments, opinions and innuendo, and it's great. Couldn't put it down.
 
Great book! *****
I have really enjoyed this book as it has science in it along with Craig Venter's life story. Any science lover should read this!
 
Meet the controversial scientist who deciphered the human genome ****
J. Craig Venter says he is one of the "leading scientists of the 21st century," and he is. Venter is a brilliant visionary and pioneer in genomic research. He was first to decode the full DNA of a living organism, the bacterium Haemophilus influenzae. Later, Venter moved up significantly in scientific class by completing the DNA sequence of the human genome. Feverishly ambitious, he is now researching ocean genomes in hopes of finding new fuel sources and of becoming the first scientist to create artificial life. Venter does nothing halfway, hence his designation by Time magazine as one of the world's 100 most influential people. Yet, in scientific circles, he has also earned some disdain as an egotistical "wild man of biotech." Many scientists see his use of his own DNA in the human genome project as a shocking lack of scientific decorum. He comes across, in his own words, as narcissistic. This self-absorption, and his pervasive portrayal of himself as an altruistic purist constantly battling bureaucratic philistines, interferes with his story about how he cracked the human genome code. Clearly, it's not easy being a genius, but it sure is interesting, and so getAbstract recommends Venter's account of his scientific achievements.

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